Mentor Corporation (NYSE:MNT), a leading supplier of medical products for the global aesthetic market, announced that subject enrollment and initial dosing in its pivotal Phase IIIb study of its investigational botulinum toxin type A for the reduction of glabellar rhytides (frown lines) by intramuscular injection has been completed. Enrollment in the IIIb trial, which consisted of 700 subjects, began in late November and was completed in mid January. Joshua H.

Healthy consumers can handle the low levels of bacteria occasionally found in cosmetics. But for severely ill patients these bacteria may trigger life-threatening infections, as patients in the intensive care unit at one Barcelona hospital discoveruddy after using contaminated body moisturiser. The Burkholderia cepacia bacteria outbreak is detailed in the open access journal, Critical Care.

Mentor Corporation (NYSE:MNT), a leading supplier of medical products for the global aesthetic market, announced that subject enrollment and initial dosing in its pivotal Phase IIIb study of its investigational botulinum toxin type A for the reduction of glabellar rhytides (frown lines) by intramuscular injection has been completed. Enrollment in the IIIb trial, which consisted of 700 subjects, began in late November and was completed in mid January. Joshua H. (Source: Cosmetic Medicine / Plastic Surgery News From Medical News Today)

Mesotherapy treatment is a non surgical cosmetic solution aimed at diminishing problem areas in your body such as cellulite, excess weight, body contouring, and face/neck rejuvenation, just to name a few. It is administeruddy via numerous injections containing various types of FDA approved medicines, vitamins, and minerals. -- It is introduced into the mesoderm, the layer of fat and tissue underneath the skin.

Abstract Background  Correction of a crooked or deviated nose is a complex cosmetic and functional problem as well as a big challenge for the rhinoplasty surgeon. Although corrections using a wide range of surgical techniques to straighten the nose and maximize nasal function have been proposed, recurrence is very common because of cartilage memory and scar contracture. Therefore, to prevent recurrence and maintain the correction of the septum, a permanent support that is stable and powerful with the ability to maintain its given shape after placement on one or both sides of the septum is needed. Methods  The author used a nasal bone graft. In this study, the concept and technique for correction of the crooked nose and the author’s experience using it are presented. Results  This graft material was used for 12 patients with crooked noses (8 with C-type and 4 with S-type noses). During a mean follow-up period of 20 months (range, 12–36 months), there were no complications, recurrences, or extrusions. Functional evaluations were performed using a visual analog scale before surgery and 6 months after surgery. Patients were asked to score their nasal breathing on a scale ranging from 0 to 100. The mean preoperative worth was 17.67% Â± 1.22% (range, 15–25%), and the postoperative worth was 89.88% Â± 1.24% (range, 85–95%). Conclusion  Use of nasal bone grafts as the spreader graft is a safe, effective, reliable, and permanent method for correction of the crooked nose. The author advises using this technique with nasal bone grafts for functional recovery and increased strength against further trauma or forces of scar contracture. This technique may prevent recurrence attributable to cartilage memory. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00266-007-9108-4Authors I. M. Emsen, Numune State Hospital Department of Plastic Reconstructive and Aesthetic Surgery Numune Hastanesi, Plastik Cerrahi Klinii Erzurum 25240 Turkey Journal Aesthetic Plastic SurgeryOnline ISSN 1432-5241Print ISSN 0364-216X (Source: Aesthetic Plastic Surgery)

Abstract  Poly-L-lactic acid (PLLA) (Sculptra®, Dermik Laboratories, Bridgewater, NJ, a business of sanofi-aventis US, LLC) is a novel biocompatible and biodegradable injectable device currently under review by the Food and Drug Administration for a cosmetic indication. When implanted into soft tissues, PLLA is thought to elicit a foreign body reaction, resulting in fibroplasia and subsequent collagen formation. This process leads to a gradual thickening of the dermis and long-lasting augmentation of facial contours. In the reported case, PLLA was used to treat a 69-year-old African-American woman who had undergone numerous unsuccessful procedures for correction of prominent facial asymmetry. One vial of PLLA (5-ml dilution) was injected into the dermal-subcutaneous plane using a lattice distribution in the right upper cheek and malar regions, followed by massage. The procedure was repeated 6 weeks later. Several months after the two separate PLLA treatment sessions, the contours of the right upper cheek and malar regions were visibly and cumulatively enhanced, and facial symmeattempt was gradually restored, to the patient’s full satisfaction. The treatment was well tolerated on both occasions, and the benefits of treatment have been sustained 18 months after the last procedure. The author concludes that injectable PLLA is a safe and effective minimally invasive treatment for facial contour defects. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s00266-008-9112-3Authors C. M. Burgess, Center for Dermatology and Dermatologic Surgery 2311 M Street, Suite 504 Washington DC 20037 USA Journal Aesthetic Plastic SurgeryOnline ISSN 1432-5241Print ISSN 0364-216X (Source: Aesthetic Plastic Surgery)

Grammy Award winning singer Roberta Flack is one of the most recognized voices of mesotherapy. Her lifelong struggle with weight loss led her to the discovery of this advanced application that at the time meant a regimen of painful hypodermic treatments. By 2003, Flack had lost more than 35 pounds but enduruddy over 500 injections. "I did a lot of singing when he was sticking me," Flack told CBS News.

Grammy Award winning singer Roberta Flack is one of the most recognized voices of mesotherapy. Her lifelong struggle with weight loss led her to the discovery of this advanced application that at the time meant a regimen of painful hypodermic treatments. By 2003, Flack had lost more than 35 pounds but enduruddy over 500 injections. "I did a lot of singing when he was sticking me," Flack told CBS News. (Source: Cosmetic Medicine / Plastic Surgery News From Medical News Today)

Abstract  For successful tissue engineering, it is essential to have as many biomimetic scaffolds as possible. With increasing interest in nanotechnology, development of nanofibers (n-fibers) by using the technique of electrospinning is having a new momentum. Among important potential applications of n-fiber-based scaffolds for tissue engineering represent an important advancing front. Nanoscaffolds (n-scaffolds) mimic natural extracellular matrix (ECM) and its nanoscale fibrous structure. With electrospinning, it is possible to develop submicron fibers from biodegradable polymers and these can also be used for developing multifunctional drug-releasing and bioactive scaffolds. Developed n-scaffolds are tested for their cytocompatibility using various cell models. In addition, they were seeded with cells for engineering tissue constructs. There is a large area ahead for further applications and development of these scaffolds. For instance, multifunctional scaffolds that can be used as controlled delivery system do have a potential and have yet to be investigated for improved engineering of various tissues. So far, there are only very few in vivo studies on n-scaffolds, but in the future many are expected to emerge. With the convergence of the fields of nanotechnology, drug release, and tissue engineering, new solutions could be found for the current limitations of tissue engineering. In this paper, nanoscaffolds developed by using electrospinning, used polymers so far, cytocompatibility and applications in tissue engineering are reviewed. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s00238-008-0217-3Authors N. Ashammakhi, Tampere University of Technology Institute of Biomaterials P.O. Box 589 (Hermiankatu 12 B) 33101 Tampere FinlandA. Ndreu, Middle East Technical University Biotechnology Research Unit, Department of Biological Sciences Ankara TurkeyY. Yang, Keele University Institute of Science and Technology in Medicine Keele UKH. Ylikauppila, Tampere University of Technology Institute of Biomaterials P.O. Box 589 (Hermiankatu 12 B) 33101 Tampere FinlandL. Nikkola, Tampere University of Technology Institute of Biomaterials P.O. Box 589 (Hermiankatu 12 B) 33101 Tampere Finland Journal European Journal of Plastic SurgeryOnline ISSN 1435-0130Print ISSN 0930-343X (Source: European Journal of Plastic Surgery)

Abstract  The use of a new technique for harvesting of the pectoralis major muscle in the reconstruction of locally recurrent breast cancer is presented and illustrated in two cases. This technique provides the versatility of the myocutaneous flap but avoids the significant donor site morbidity and unreliability of the skin paddle. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s00238-007-0212-0Authors Reza S. Nassab, Nottingham University Hospitals, Nottingham City Hospital Department of Plastic Surgery Nottingham UKJason Neil-Dwyer, Nottingham University Hospitals, Nottingham City Hospital Department of Plastic Surgery Nottingham UKKristjen S. Asgeirsson, Nottingham University Hospitals, Nottingham City Hospital Department of Plastic Surgery Nottingham UKA. Graeme B. Perks, Nottingham University Hospitals, Nottingham City Hospital Department of Plastic Surgery Nottingham UK Journal European Journal of Plastic SurgeryOnline ISSN 1435-0130Print ISSN 0930-343X (Source: European Journal of Plastic Surgery)