Abstract Background  Over the past few years, treatment of burn scars with lipofilling has shown encouraging clinical results in terms of texture, color, softness, and quality of skin patterns. This clinical application has been widened to include treatment for scars resulting from surgical correction of cicatricial ectropion. In fact, although standard surgery with flaps and skin grafts can grant significant functional and cosmetic improvements, these often are not complete because of secondary surgical scars. Methods  The case of a 43-year-old man with cicatricial outcomes from chemical burns and subsequent surgical repair of medial ectropion in the lower eyelid is reported. The scar area was treated with injection of adipose tissue harvested from abdominal subcutaneous fat and processed according to Coleman’s technique. Results  At the 1-year follow-up assessment after lipostructure, the patient no longer reported xeroftalmia and epiphora. He had experienced complete functional recovery with excellent cosmetic results. Conclusions  Lipostructure of cicatricial ectropion seems to complete and improve the results of the standard surgical approach, and its long-lasting benefits are in keeping with the theoretical basis of this procedure. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s00266-008-9117-yAuthors F. Caviggioli, Università degli Studi di Milano, IRCCS Istituto Clinico Humanitas Cattedra di Chirurgia Plastica–Unità Operativa di Chirurgia Plastica 2 Via Manzoni 56 20089 Rozzano ItalyF. Klinger, Università degli Studi di Milano, IRCCS Istituto Clinico Humanitas Cattedra di Chirurgia Plastica–Unità Operativa di Chirurgia Plastica 2 Via Manzoni 56 20089 Rozzano ItalyF. Villani, Università degli Studi di Milano, IRCCS Istituto Clinico Humanitas Cattedra di Chirurgia Plastica–Unità Operativa di Chirurgia Plastica 2 Via Manzoni 56 20089 Rozzano ItalyC. Fossati, Università degli Studi di Milano, IRCCS Istituto Clinico Humanitas Cattedra di Chirurgia Plastica–Unità Operativa di Chirurgia Plastica 2 Via Manzoni 56 20089 Rozzano ItalyV. Vinci, Università degli Studi di Milano, IRCCS Istituto Clinico Humanitas Cattedra di Chirurgia Plastica–Unità Operativa di Chirurgia Plastica 2 Via Manzoni 56 20089 Rozzano ItalyM. Klinger, Università degli Studi di Milano, IRCCS Istituto Clinico Humanitas Cattedra di Chirurgia Plastica–Unità Operativa di Chirurgia Plastica 2 Via Manzoni 56 20089 Rozzano Italy Journal Aesthetic Plastic SurgeryOnline ISSN 1432-5241Print ISSN 0364-216X (Source: Aesthetic Plastic Surgery)